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Even to add or change just a single file, an overall copy of the virtual machine needs to be assembled and deployed.
Moreover it is difficult, if not impossible, to reuse pieces of software or data inside a virtual machine.
This prevents conflicts with other installed programs in the hosting environment, and guarantees that each process runs in a predictable system configuration that cannot change over time due to misconfigured software, system updates or programming errors.
A container only requires a fraction of a second to start and many instances can run in the same hosting environment.
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The most obvious advantage of this approach is to replace the tedious installation of numerous pieces of software, with complex dependencies, by simply downloading a single pre-built ready-to-run image containing all the software and the required configuration.
In this work, we assess the impact of Docker containers on the performance of genomic pipelines using a realistic computational biology usage scenario based on the re-computation of selected subsets of the mouse ENCODE analysis.
This makes it easy to distribute and execute pipelines in a portable manner across a wide range of computing platforms.
Thus, the question that arises is to what extent the use of Docker containers might affect the performance of these pipelines.
Here we address this question and conclude that Docker containers have only a minor impact on the performance of common genomic pipelines, which is negligible when the executed jobs are long in terms of computational time.
Genomic pipelines usually rely on a combination of several pieces of third party research software.
Theoretical Damage Per Minute Nominal DPM: 1038.6 50% Crew: 815.85 75% Crew: 927.45 100% Crew: 1038.6 100% Crew Vents: 1062.9 Rammer: 1153.8 Both: 1180.8 Both and Bi A: 1203.75 Both and Max Crew %: 1255.5 Advantageous Damage Per Minute First-shot DPM: 1083.6 50% Crew: 860.85 75% Crew: 972.45 100% Crew: 1083.6 100% Crew Rammer: 1198.8 Vents: 1107.9 Both: 1225.8 Both and Bi A: 1248.75 Both and Max Crew %: 1300.5 See here, here, or here for more information. The vehicle saw service in the Czechoslovakian army as a cavalry and infantry support vehicle. It was used for the remainder of the war by other countries and as a training tank in Bulgaria into the 1950s. The letter (t) stood for tschechisch (German: "Czech").